Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.32 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19430288 | 0.91 | AOC3 (0.38) | PARP1P2RX7PARP2GPR84WNK1 | |
| SCHEMBL19429857 | 0.89 | PRMT6 (0.39) | PRMT6WNK1MOKPRMT1KDM4E | |
| SCHEMBL19430238 | 0.88 | PRMT6 (0.39) | PRMT6WNK1MOK | |
| SCHEMBL19429860 | 0.88 | SMN1; SMN2 (0.44) | PRMT6PARP1KDM4EALDH1A1LMNA | |
| SCHEMBL19429973 | 0.87 | PRMT6 (0.48) | PRMT6MOKKDM4EALDH1A1LMNA | |
| SCHEMBL19430109 | 0.85 | PRMT6 (0.37) | PRMT6WNK1MOKPRMT1 | |
| SCHEMBL19429963 | 0.85 | PRMT6 (0.37) | PRMT6WNK1MOK | |
| SCHEMBL19430139 | 0.85 | PRMT6 (0.41) | PRMT6MOKPRMT1 | |
| SCHEMBL19429853 | 0.80 | AOC3 (0.41) | WNK1KDM4EALDH1A1LMNAHTT | |
| SCHEMBL19430247 | 0.79 | PRMT6 (0.38) | PRMT6MOKPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170280720-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170280720-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | PRMT1, PRMT3, PRMT5 | PRMT6 4/4885PARP1 780/4885P2RX7 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.