Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436976 | 1.00 | MAPT (0.56) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL847404 | 0.79 | SMN1; SMN2 (0.57) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL7666031 | 0.77 | PLAAT5 (0.65) | HTTMEN1KMT2APOLBCYP2D6 | |
| SCHEMBL2087431 | 0.76 | ALDH1A1 (0.62) | LMNAALDH1A1POLBHPGDCYP2D6 | |
| SCHEMBL8991793 | 0.76 | MAPT (0.69) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL3363874 | 0.75 | CYP2D6 (0.52) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL3057351 | 0.75 | LMNA (0.55) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL3057356 | 0.75 | LMNA (0.55) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL7216546 | 0.75 | KMT2A (0.46) | HTTMEN1KMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL20547794 | 0.74 | ALDH1A1 (0.60) | LMNAALDH1A1POLBHPGDCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017176930-A1 | DIPHENYLACRYLIC ACID DERIVATIVES THAT PROMOTE BONE AND CARTILAGE GROWTH | EMORY UNIVERSITY (US) | 2017-10-12 | — | — | WO | disclosed |