Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378837 | 0.82 | LMNA (0.48) | TSHRFABP4FABP5LMNAMAPK1 | |
| SCHEMBL965996 | 0.82 | LMNA (0.48) | TSHRFABP4FABP5LMNAMAPK1 | |
| SCHEMBL31681943 | 0.82 | LMNA (0.48) | TSHRFABP4FABP5LMNAMAPK1 | |
| SCHEMBL1286264 | 0.82 | LMNA (0.48) | TSHRFABP4FABP5LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL7291333 | 0.80 | LMNA (0.47) | TSHRFABP4FABP5LMNAMAPK1 | |
| SCHEMBL18522893 | 0.80 | GABRA1 (0.43) | TSHRLMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8854194 | 0.79 | LMNA (0.41) | FABP4FABP5LMNAMAPK1KMT2A | |
| SCHEMBL2349279 | 0.78 | MEN1 (0.53) | TSHRFABP4FABP5LMNAMAPK1 | |
| SCHEMBL3781319 | 0.77 | TSHR (0.48) | TSHRLMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL19437480 | 0.76 | FABP4 (0.45) | TSHRFABP4FABP5LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109219601-B | Method for preparing optically active beraprost | 奇诺因药物和化学工厂私人有限公司 | 2022-08-09 | — | — | CN | claimed |
| EP-3440065-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE BERAPROST | EUROAPI HUNGARY LLC (HU) | 2022-06-08 | — | — | EP | claimed |
| US-10421737-B2 | Process for the preparation of optically active Beraprost | CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIVATE COMPANY LTD. (HU) | 2019-09-24 | — | — | US | claimed |
| EP-3440065-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE BERAPROST | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2019-02-13 | — | — | EP | claimed |
| WO-2017174439-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE BERAPROST | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-10-12 | — | — | WO | claimed |
| CN-109219601-B | Method for preparing optically active beraprost | 奇诺因药物和化学工厂私人有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-3440065-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE BERAPROST | EUROAPI HUNGARY LLC (HU) | 2022-06-08 | — | — | EP | disclosed |
| US-10421737-B2 | Process for the preparation of optically active Beraprost | CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIVATE COMPANY LTD. (HU) | 2019-09-24 | — | — | US | disclosed |
| EP-3440065-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE BERAPROST | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2019-02-13 | — | — | EP | disclosed |
| WO-2017174439-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE BERAPROST | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421737-B2 | Process for the preparation of optically active Beraprost | CYP51A1, DDOST, SQLE | TSHR 4077/4885FABP4 2340/4885FABP5 2383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.