SCHEMBL19444971

SCHEMBL19444971

O=P(c1ccccc1)(c1ccc(-c2ccccc2)cn1)c1ccc(-c2ccccc2)cn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 5/20 0.41
NPC1 O15118 2/20 0.41
NFKB1 P19838 2/20 0.41
RAB9A P51151 2/20 0.41
NFKB2 Q00653 2/20 0.41
RELA Q04206 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.37
MMP8 P22894 1/20 0.36
MMP14 P50281 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CHEK1 O14757 1/20 0.36
AURKA O14965 1/20 0.36
DAPK3 O43293 1/20 0.36
PRKD3 O94806 1/20 0.36
MAP4K4 O95819 1/20 0.36
ABL1 P00519 1/20 0.36
NTRK1 P04629 1/20 0.36
CSF1R P07333 1/20 0.36
RET P07949 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19448980 0.90 NPC1 (0.45) HIF1ANPC1NFKB1RAB9ANFKB2
SCHEMBL18253843 0.80 DHODH (0.33) HIF1ANPC1RAB9ASMN1; SMN2DYRK1A
SCHEMBL13454344 0.80 NPC1 (0.51) NPC1NFKB1RAB9ANFKB2RELA
SCHEMBL16161040 0.79 NPC1 (0.47) HIF1ANPC1NFKB1RAB9ANFKB2
SCHEMBL20108878 0.78 PARP1 (0.40) RAB9AALDH1A1MAPTNPSR1MEN1
SCHEMBL19797419 0.78 ALDH1A1 (0.44) NPC1NFKB1RAB9ANFKB2RELA
SCHEMBL30382826 0.78 CA1 (0.44) NPC1NFKB1RAB9ANFKB2RELA
SCHEMBL16161071 0.78 NPSR1 (0.40) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL9001586 0.77 LMNA (0.54) NPC1RAB9ALMNAMMP8MMP14
SCHEMBL19448976 0.77 LMNA (0.54) NPC1RAB9ALMNAMMP8MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10756274-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-25 US disclosed
US-20170294587-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
US-20170294587-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
EP-3229289-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-10-11 EP disclosed