Sugi Predict

Sugi Predict / Compounds / SCHEMBL20108878

SCHEMBL20108878

SCHEMBL20108878

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc3ccc4ccc(-c5ccccc5)nc4c3n2)cn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PARP1 P09874 1/20 0.40
▸ KCNA5 P22460 2/20 0.34
▸ KCNN4 O15554 1/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ PTPN2 P17706 1/20 0.34
▸ PTPN1 P18031 1/20 0.34
▸ HPGDS O60760 1/20 0.33
▸ LDHA P00338 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ MKNK2 Q9HBH9 1/20 0.33
▸ TOP1 P11387 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20108898 0.89 NOS1 (0.39) PARP1MEN1KMT2ARAB9ATOP1
SCHEMBL20108872 0.89 CCR1 (0.41) PARP1KCNA5KCNN4TOP1ALDH1A1
SCHEMBL20108851 0.88 PARP1 (0.44) PARP1KCNA5MEN1KMT2ARAB9A
SCHEMBL17403775 0.85 PARP1 (0.46) PARP1MEN1KMT2ARAB9ATOP1
SCHEMBL20108903 0.80 CYP1A1 (0.37) PARP1RAB9APTPN2PTPN1HPGDS
SCHEMBL17174127 0.79 PARP1 (0.46) PARP1MEN1KMT2ARAB9ATOP1
SCHEMBL17174105 0.79 PARP1 (0.46) PARP1MEN1KMT2ARAB9ATOP1
SCHEMBL17174111 0.78 PARP1 (0.41) PARP1KCNA5KCNN4MEN1KMT2A
SCHEMBL19444971 0.78 HIF1A (0.41) MEN1KMT2ARAB9AALDH1A1MAPT
SCHEMBL14020765 0.78 PARP1 (0.47) PARP1MEN1KMT2ARAB9ATOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX PARP1 2652/4885KCNA5 1353/4885KCNN4 590/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX PARP1 2652/4885KCNA5 1353/4885KCNN4 590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.