Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445708 | 0.80 | KLKB1 (0.39) | KDM4CCA1CA2MAPTLMNA | |
| SCHEMBL19445586 | 0.74 | TERT (0.41) | KDM4CRAB9AMEN1GAAKMT2A | |
| SCHEMBL24475446 | 0.67 | SPHK1 (0.49) | SPHK1 | |
| SCHEMBL27431579 | 0.67 | SPHK1 (0.49) | SPHK1 | |
| SCHEMBL24086378 | 0.67 | SPHK1 (0.49) | MAPTLMNASPHK1L3MBTL1RAB9A | |
| SCHEMBL13437223 | 0.67 | EPHX1 (0.47) | MAPTLMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL19445593 | 0.66 | HSD17B10 (0.41) | KDM4CACHEBACE1CA1CA2 | |
| SCHEMBL26445334 | 0.66 | TRPV1 (0.48) | CA1CA2MAPTSPHK1ALOX5 | |
| SCHEMBL22602618 | 0.66 | TRPV1 (0.48) | CA1CA2MAPTSPHK1ALOX5 | |
| SCHEMBL19445622 | 0.65 | ERAP2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |