Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.37 |
| ▸ | EGFR | P00533 | 5/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445708 | 0.86 | KLKB1 (0.39) | TERTKMT2AMEN1KDM4C | |
| SCHEMBL19445622 | 0.75 | ERAP2 (0.43) | TERT | |
| SCHEMBL19445494 | 0.74 | KDM4C (0.35) | KMT2AMEN1GAAKDM4CRAB9A | |
| SCHEMBL19445181 | 0.71 | MMP2 (0.42) | KMT2AMEN1 | |
| SCHEMBL8365170 | 0.69 | RAB9A (0.49) | HDAC1HDAC2KMT2AMEN1GAA | |
| SCHEMBL19445846 | 0.69 | ERAP2 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10262149 | 0.69 | ERAP2 (0.43) | TERT | |
| SCHEMBL27676821 | 0.68 | CYP3A4 (0.53) | KMT2AMEN1GAAKDM4CNPC1 | |
| SCHEMBL19445517 | 0.68 | NPY4R (0.40) | — | |
| SCHEMBL19445627 | 0.68 | NPC1 (0.39) | TERTHDAC3EGFRHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |