Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826405 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KEAP1LMNAKDM4EMEN1 | |
| SCHEMBL31050324 | 0.76 | ERN1 (0.52) | ALDH1A1LMNACA12CA9 | |
| SCHEMBL7820970 | 0.76 | ERN1 (0.52) | ALDH1A1TDP1HPGDHSD17B10 | |
| SCHEMBL1017248 | 0.76 | ERN1 (0.52) | ALDH1A1LMNACA12CA9 | |
| SCHEMBL30033864 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KEAP1LMNAKDM4EMEN1 | |
| SCHEMBL29950830 | 0.76 | TYR (0.39) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL28667906 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4EMEN1THRB | |
| SCHEMBL11664879 | 0.73 | LMNA (0.46) | ALDH1A1PTGS1LMNAKDM4EPOLB | |
| SCHEMBL7817772 | 0.73 | MAPT (0.39) | ALDH1A1LMNAKDM4EMEN1BLM | |
| SCHEMBL21587338 | 0.73 | TYR (0.53) | ALDH1A1PTGS1LMNAKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |