Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | QPCT | Q16769 | 3/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | C5 | P01031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13973873 | 0.82 | LMNA (0.42) | LMNAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL19445763 | 0.81 | LMNA (0.40) | LMNAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL12515235 | 0.77 | LMNA (0.41) | LMNAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL13815082 | 0.76 | AAK1 (0.44) | LMNAMEN1KMT2APOLB | |
| SCHEMBL19445850 | 0.76 | NPC1 (0.42) | LMNAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL19445682 | 0.76 | SMN1; SMN2 (0.40) | LMNAKMT2ASMN1; SMN2POLBKDM4E | |
| SCHEMBL19445573 | 0.75 | LMNA (0.39) | LMNAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL15317942 | 0.73 | LMNA (0.46) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13973703 | 0.73 | HSD17B10 (0.40) | LMNAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL10262220 | 0.72 | ALDH1A1 (0.41) | LMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |