Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445593 | 0.85 | HSD17B10 (0.41) | LMNAPOLBTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL19445753 | 0.85 | HSD17B10 (0.48) | LMNATSHRHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL19445682 | 0.85 | SMN1; SMN2 (0.40) | LMNAPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL19445573 | 0.84 | LMNA (0.39) | LMNAPOLBTSHRHSD17B10ALDH1A1 | |
| SCHEMBL13973873 | 0.84 | LMNA (0.42) | LMNAPOLBHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL19445591 | 0.81 | TSHR (0.39) | LMNATSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL19445628 | 0.81 | LMNA (0.38) | LMNAPOLBKDM4ESMN1; SMN2QPCT | |
| SCHEMBL13815093 | 0.81 | AAK1 (0.43) | LMNAPOLB | |
| SCHEMBL19445664 | 0.78 | NPY4R (0.41) | TSHR | |
| SCHEMBL19445850 | 0.77 | NPC1 (0.42) | LMNAPOLBTSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |