Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 8/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | NPPA | P01160 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10262527 | 0.92 | LNPEP (0.52) | LNPEPERAP2MMEFPR2TSHR | |
| SCHEMBL19486132 | 0.91 | LNPEP (0.51) | LNPEPERAP2MMEFPR2TSHR | |
| SCHEMBL21371569 | 0.91 | LNPEP (0.51) | LNPEPERAP2MMEFPR2TSHR | |
| SCHEMBL19445640 | 0.86 | MMP2 (0.41) | LNPEPERAP2TSHRERAP1MMP2 | |
| SCHEMBL12515368 | 0.85 | KLKB1 (0.41) | LNPEPERAP2TSHRERAP1MMP2 | |
| SCHEMBL19445676 | 0.85 | FPR2 (0.52) | LNPEPERAP2FPR2TSHRERAP1 | |
| SCHEMBL10263498 | 0.85 | FPR2 (0.52) | LNPEPERAP2FPR2TSHRERAP1 | |
| SCHEMBL10260986 | 0.85 | FPR2 (0.52) | LNPEPERAP2FPR2TSHRERAP1 | |
| SCHEMBL21371597 | 0.84 | KLKB1 (0.41) | LNPEPERAP2TSHRERAP1MMP2 | |
| SCHEMBL19445715 | 0.84 | KLKB1 (0.41) | LNPEPERAP2TSHRERAP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |