Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | Q9HBH1 | 1/20 | 0.43 | |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445698 | 0.79 | LMNA (0.44) | LMNACA1CA2CA7CA14 | |
| SCHEMBL19445708 | 0.74 | KLKB1 (0.39) | LMNACA1CA2PDFMEN1 | |
| SCHEMBL15894581 | 0.69 | EGFR (0.55) | CA1CA2CA7CA14EGFR | |
| SCHEMBL19445622 | 0.69 | ERAP2 (0.43) | — | |
| SCHEMBL21945409 | 0.69 | TAS1R3 (0.52) | LMNACA1CA2CA7CA14 | |
| SCHEMBL18882713 | 0.69 | MEN1 (0.72) | LMNACA1CA2CA7CA14 | |
| SCHEMBL11202803 | 0.68 | CA12 (0.49) | LMNACA1CA2EGFRMEN1 | |
| SCHEMBL2761543 | 0.68 | MEN1 (0.64) | LMNACA1CA2CA7CA14 | |
| SCHEMBL6009620 | 0.67 | CA1 (0.57) | LMNACA1CA2CA7CA14 | |
| SCHEMBL11488933 | 0.67 | CA1 (0.55) | LMNACA1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |