Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19214490 | 0.84 | ALDH1A1 (0.52) | NPC1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL19445870 | 0.84 | ALDH1A1 (0.68) | MAPTPKMRAB9AALDH1A1KDM4E | |
| SCHEMBL19445568 | 0.78 | MAPK14 (0.38) | NPC1RAB9AALDH1A1KDM4EHTT | |
| SCHEMBL19445570 | 0.78 | MAPK14 (0.38) | NPC1RAB9AALDH1A1KDM4EHTT | |
| SCHEMBL19445652 | 0.78 | MAPK14 (0.38) | NPC1RAB9AALDH1A1KDM4EHTT | |
| SCHEMBL19445737 | 0.77 | ALDH1A1 (0.46) | PKMRAB9AALDH1A1 | |
| SCHEMBL13978402 | 0.76 | NPC1 (0.62) | NPC1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL29859151 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KDM4EHTTHPGDSMN1; SMN2 | |
| SCHEMBL19219830 | 0.73 | ALDH1A1 (0.53) | MAPTRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL12444109 | 0.73 | ALDH1A1 (0.53) | NPC1MAPTRAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |