Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639778 | 0.75 | NAAA (0.60) | ALDH1A1KDM4EHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL1856511 | 0.74 | ACMSD (0.53) | ALDH1A1KDM4ESMN1; SMN2ACMSDQDPR | |
| SCHEMBL21046542 | 0.74 | HTT (0.66) | ALDH1A1KDM4EHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL19445828 | 0.74 | NPC1 (0.53) | ALDH1A1KDM4EHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL11216405 | 0.73 | KDM4E (0.68) | ALDH1A1KDM4EHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL29159056 | 0.73 | CHEK1 (0.43) | ALDH1A1KDM4EHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL2313791 | 0.73 | PBK (0.56) | HTTSMN1; SMN2AOX1 | |
| SCHEMBL27881584 | 0.72 | CA12 (0.59) | ACMSDKMT2AQDPR | |
| SCHEMBL24163465 | 0.71 | HTT (0.48) | ALDH1A1KDM4EHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL10820432 | 0.71 | CDK1 (0.74) | ALDH1A1KDM4EHTTCYP1A2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398097-B2 | WDR5-MYC inhibitors | VANDERBILT UNIVERSITY (US) | 2025-08-26 | — | — | US | disclosed |
| US-20220289673-A1 | WDR5-MYC INHIBITORS | VANDERBILT UNIVERSITY | 2022-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220289673-A1 | WDR5-MYC INHIBITORS | MYC, WDR5, MYCBP | ALDH1A1 3953/4885KDM4E 344/4885HTT 1364/4885 |
| US-12398097-B2 | WDR5-MYC inhibitors | MYC, WDR5, MYCBP | ALDH1A1 3953/4885KDM4E 344/4885HTT 1364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.