Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | C1S | P09871 | 2/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366256 | 0.90 | ALDH1A1 (0.46) | ALDH1A1GBA1PKMLMNAKDM4E | |
| SCHEMBL2366540 | 0.83 | ABL1 (0.44) | ALDH1A1GBA1KDM4ESLC6A7KMT2A | |
| SCHEMBL14686547 | 0.82 | MEN1 (0.44) | ALDH1A1LMNAKDM4ESLC6A7MEN1 | |
| SCHEMBL14687647 | 0.81 | MEN1 (0.44) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL14686883 | 0.81 | MEN1 (0.64) | ALDH1A1PKMLMNAKDM4EMEN1 | |
| SCHEMBL27848280 | 0.81 | ALDH1A1 (0.43) | ALDH1A1GBA1LMNAKDM4EMEN1 | |
| SCHEMBL14687200 | 0.81 | MEN1 (0.43) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL14687293 | 0.81 | ALDH1A1 (0.53) | ALDH1A1GBA1LMNAKDM4EMEN1 | |
| SCHEMBL2365769 | 0.81 | KMT2A (0.43) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL20134799 | 0.80 | ALDH1A1 (0.39) | ALDH1A1GBA1LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565182-B1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-10-11 | — | — | EP | disclosed |