Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27909753 | 0.98 | ALDH1A1 (0.42) | ALDH1A1MAPTGFERGAALMNA | |
| SCHEMBL14735613 | 0.89 | KMT2A (0.38) | ALDH1A1KMT2AMEN1GBA1KDM4E | |
| SCHEMBL2366187 | 0.81 | GBA1 (0.47) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL19446822 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL27848283 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL2366256 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAGBA1KDM4E | |
| SCHEMBL19446710 | 0.79 | HRH4 (0.51) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL14687522 | 0.77 | GBA1 (0.42) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL2366189 | 0.77 | GPR6 (0.52) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL12240392 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1MAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239152-B | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP. (JP) | 2014-10-29 | — | — | CN | disclosed |
| CN-102971291-A | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2013-03-13 | — | — | CN | disclosed |
| CN-102239152-A | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2011-11-09 | — | — | CN | disclosed |