Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 3/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15676738 | 0.83 | MEN1 (0.74) | THRBMEN1KMT2ARXFP1MAPT | |
| SCHEMBL15676754 | 0.82 | NPC1 (0.61) | THRBMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL19087072 | 0.82 | BCAT2 (0.63) | THRBMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL19087055 | 0.81 | GRM5 (0.65) | THRBMEN1KMT2ASMN1; SMN2BRAF | |
| SCHEMBL12228481 | 0.79 | HDAC1 (0.61) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL19116772 | 0.78 | GRM5 (0.64) | MEN1KMT2ABRAFNPC1RAB9A | |
| SCHEMBL19087022 | 0.78 | GRM5 (0.67) | THRBMEN1KMT2ARXFP1BRAF | |
| SCHEMBL19117169 | 0.78 | TRPV1 (0.58) | SMN1; SMN2NPC1RAB9ATRPV1KCNK3 | |
| SCHEMBL23015732 | 0.78 | TDP1 (0.78) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL4317671 | 0.77 | CSF1R (0.53) | BRAFMAPTGSK3BCYP2C9GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848610-B1 | Inhibitors of kinase activity | YM BIOSCIENCES AUSTRALIA PTY (AU) | 2017-10-11 | — | — | EP | disclosed |