Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991307 | 1.00 | LMNA (0.59) | LMNADNM1TSHRTHRBALDH1A1 | |
| SCHEMBL5488763 | 1.00 | LMNA (0.59) | LMNADNM1TSHRTHRBALDH1A1 | |
| SCHEMBL11821234 | 1.00 | LMNA (0.59) | LMNADNM1TSHRTHRBALDH1A1 | |
| SCHEMBL10582089 | 1.00 | LMNA (0.59) | LMNADNM1TSHRTHRBALDH1A1 | |
| SCHEMBL1697645 | 0.97 | LMNA (0.55) | LMNADNM1TSHRTHRBALDH1A1 | |
| SCHEMBL17822464 | 0.97 | LMNA (0.62) | LMNADNM1TSHRTHRBALDH1A1 | |
| SCHEMBL3634317 | 0.97 | LMNA (0.62) | LMNADNM1TSHRTHRBALDH1A1 | |
| SCHEMBL8026611 | 0.97 | LMNA (0.62) | LMNADNM1TSHRTHRBALDH1A1 | |
| SCHEMBL11330180 | 0.97 | LMNA (0.62) | LMNADNM1TSHRTHRBALDH1A1 | |
| SCHEMBL4949893 | 0.97 | LMNA (0.62) | LMNADNM1TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130457-A1 | Wax-Based Emulsion for the Treatment of Dry Eye Conditions | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| WO-2010017365-A1 | WAX-BASED EMULSION FOR THE TREATMENT OF DRY EYE CONDITIONS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | WO | disclosed |