Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322511 | 1.00 | GLO1 (0.50) | GLO1ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL222772 | 1.00 | GLO1 (0.50) | GLO1ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL31278293 | 0.89 | GLO1 (0.45) | GLO1ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL937816 | 0.86 | GLO1 (0.42) | GLO1ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL20271509 | 0.86 | GLO1 (0.42) | GLO1ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL11646015 | 0.85 | HCAR2 (0.39) | GLO1ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL317281 | 0.84 | ALDH1A1 (0.48) | GLO1ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL3034863 | 0.84 | ALDH1A1 (0.45) | GLO1ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL11455383 | 0.84 | GLO1 (0.41) | GLO1ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL11006159 | 0.84 | GLO1 (0.41) | GLO1ALDH1A1LMNAHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794611-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2017-10-11 | — | — | EP | disclosed |