SCHEMBL317281

SCHEMBL317281

CCOCCOC=C(C)C(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.48
TSHR P16473 2/20 0.48
THRB P10828 1/20 0.47
GLO1 Q04760 1/20 0.41
NPSR1 Q6W5P4 2/20 0.37
LMNA P02545 3/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
S1PR4 O95977 1/20 0.37
S1PR1 P21453 1/20 0.37
MAPK1 P28482 1/20 0.37
CYP2D6 P10635 2/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
TRPA1 O75762 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28767141 0.98 ALDH1A1 (0.47) ALDH1A1TSHRTHRBGLO1NPSR1
SCHEMBL22501011 0.88 GLO1 (0.38) ALDH1A1TSHRTHRBGLO1NPSR1
SCHEMBL27804140 0.88 GLO1 (0.38) ALDH1A1TSHRTHRBGLO1NPSR1
SCHEMBL2540770 0.88 GLO1 (0.38) ALDH1A1TSHRTHRBGLO1NPSR1
SCHEMBL29060504 0.86 ALDH1A1 (0.40) ALDH1A1TSHRTHRBGLO1NPSR1
SCHEMBL1035097 0.85 GLO1 (0.41) ALDH1A1TSHRTHRBGLO1NPSR1
SCHEMBL23152541 0.85 THRB (0.38) ALDH1A1TSHRTHRBGLO1NPSR1
SCHEMBL19447665 0.84 GLO1 (0.50) ALDH1A1TSHRGLO1NPSR1LMNA
SCHEMBL322511 0.84 GLO1 (0.50) ALDH1A1TSHRGLO1NPSR1LMNA
SCHEMBL222772 0.84 GLO1 (0.50) ALDH1A1TSHRGLO1NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114381156-B Metal oxide dispersion composition, method for producing same, film composition containing same, optical film, and optical element 凯斯科技股份有限公司 2024-03-12 CN claimed
CN-114381156-A Metal oxide dispersion composition, method for producing same, film composition containing same, optical film, and optical element 凯斯科技股份有限公司 2022-04-22 CN claimed
EP-3555677-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS Benz Research And Development Corporation (US) 2019-10-23 EP claimed
WO-2018112180-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 WO claimed
US-20170181847-A1 POLYMERIC COMPOSITION FOR OCULAR DEVICES DAVE, Jagrat Natavar (IN) 2017-06-29 US claimed
EP-2591025-A2 POLYMERIC COMPOSITION FOR OCULAR DEVICES Polymer Technologies International (EOU) (IN) 2013-05-15 EP claimed
WO-2012004744-A2 POLYMERIC COMPOSITION FOR OCULAR DEVICES POLYMER TECHNOLOGIES INTERNATIONAL (EOU) (IN) 2012-01-12 WO claimed
US-6617086-B2 Providing on substrate a layer of a negative photoresist comprising a polymer having methacrylate recurring groups; imagewise exposing layer to irradiation; developing photoresist by removing portions of layer not exposed INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-09-09 US claimed
US-20020123010-A1 Forming a pattern of a negative photoresist INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2002-09-05 US claimed
US-11925686-B2 Materials for phototherapies of ophthalmic diseases EYEBRIGHT MEDICAL TECHNOLOGY (BEIJING) CO., LTD. (CN) 2024-03-12 US disclosed
US-11352513-B2 UV curable inkjet inks for printing on glass AGFA NV (BE) 2022-06-07 US disclosed
EP-3983419-A1 SILYLATED ADDUCTS, SILYLATED POLYMERS AND COMPOSITIONS COMPRISING SAME Bostik SA (FR) 2022-04-20 EP disclosed
CN-114249956-A Surface-modified metal oxide nanoparticle dispersion composition, method for producing same, film composition, and optical film 凯斯科技股份有限公司 2022-03-29 CN disclosed
EP-3555677-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS Benz Research And Development Corporation (US) 2019-10-23 EP disclosed
US-20130109779-A1 POLYMERIC COMPOSITION FOR OCULAR DEVICES POLYMER TECHNOLOGIES INTERNATIONAL (EOU) (IN) 2013-05-02 US disclosed
WO-2012004746-A2 REFRACTIVE-DIFFRACTIVE OPHTHALMIC DEVICE AND COMPOSITIONS USEFUL FOR PRODUCING SAME POLYMER TECHNOLOGIES INTERNATIONAL (EOU) (IN) 2012-01-12 WO disclosed
WO-2012004744-A2 POLYMERIC COMPOSITION FOR OCULAR DEVICES POLYMER TECHNOLOGIES INTERNATIONAL (EOU) (IN) 2012-01-12 WO disclosed
US-5147923-A Water-swellable random copolymers of N, N-dimethylacrylamide and (cyclo)aliphatic or aromatic acrylic esters having low cloud points CIBA-GEIGY CORPORATION (US) 1992-09-15 US disclosed
US-5104954-A Swellable random copolymers of N,N-dimethylacrylamide and acrylic esters having reversible cloud points; for heat activated sunscreens CIBA-GEIGY CORPORATION (US) 1992-04-14 US disclosed
US-5057560-A Thermotropic copolymer hydrogels from N,N-dimethylacrylamide and methoxy-ethyl (meth) acrylate CIBA-GEIGY CORPORATION (US) 1991-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11925686-B2 Materials for phototherapies of ophthalmic diseases ALDH1A2, LCP1, PDE6C ALDH1A1 1036/4885TSHR 3777/4885THRB 4635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.