Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 13/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.62 |
| ▸ | USP2 | O75604 | 11/20 | 0.62 |
| ▸ | MEN1 | O00255 | 11/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.60 |
| ▸ | CASP1 | P29466 | 7/20 | 0.60 |
| ▸ | CASP7 | P55210 | 6/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28694505 | 0.81 | MAPT (0.68) | USP2MEN1KMT2AALDH1A1MAPT | |
| Isocryptolepine SCHEMBL29349681 | 0.79 | ALDH1A1 (0.54) | CYP3A4CYP1A2USP2MEN1KMT2A | |
| Isocryptolepine SCHEMBL9390637 | 0.79 | ALDH1A1 (0.54) | CYP3A4CYP1A2USP2MEN1KMT2A | |
| SCHEMBL7815250 | 0.78 | MAPT (0.54) | CYP3A4CYP1A2USP2MEN1KMT2A | |
| SCHEMBL31448409 | 0.78 | MAPT (0.71) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7815125 | 0.77 | RAB9A (0.67) | CYP3A4CYP1A2USP2MEN1KMT2A | |
| SCHEMBL19448879 | 0.77 | MAPT (1.00) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| Acetic Acid SCHEMBL7815108 | 0.76 | CAMK2D (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14006985 | 0.75 | ALDH1A1 (1.00) | CYP3A4CYP1A2USP2MEN1KMT2A | |
| SCHEMBL30139977 | 0.73 | KDM4E (0.82) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | ASTRA AKTIEBOLAG, A SWEDEN CORPORATION | 2001-09-27 | — | — | US | disclosed |
| US-6271231-B1 | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2001-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | CSNK1A1, CSNK1G1, CSNK2A1 | CYP3A4 790/4885CYP1A2 477/4885USP2 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.