Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD1 | O95696 | 6/20 | 0.39 |
| ▸ | BRPF3 | Q9ULD4 | 5/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.36 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17576492 | 0.82 | BRPF1 (0.52) | BRPF1ALDH1A1BRD1BRPF3HDAC8 | |
| SCHEMBL19448890 | 0.81 | BRPF1 (0.62) | BRPF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL5752773 | 0.80 | ATAD2 (0.48) | BRPF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL19448882 | 0.76 | BRPF1 (0.50) | BRPF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL24637972 | 0.76 | BRPF1 (0.54) | BRPF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL9027928 | 0.72 | ATAD2 (0.64) | BRPF1KDM4EALDH1A1SMN1; SMN2BRD1 | |
| SCHEMBL19448891 | 0.72 | BRPF1 (0.54) | BRPF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL22421732 | 0.70 | BRPF1 (0.61) | BRPF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL22421767 | 0.70 | BRPF1 (0.57) | BRPF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL19869651 | 0.70 | BRPF1 (0.39) | BRPF1KDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170291875-A1 | QUINOLONES AS INHIBITORS OF CLASS IV BROMODOMAIN PROTEINS | UCL BUSINESS PLC (GB) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291875-A1 | QUINOLONES AS INHIBITORS OF CLASS IV BROMODOMAIN PROTEINS | BRD4, BRPF3, BRD3 | BRPF1 104/4885KDM4E 401/4885ALDH1A1 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.