Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17560784 | 0.99 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL17560785 | 0.99 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| SCHEMBL16224372 | 0.96 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL16212398 | 0.94 | SMN1; SMN2 (0.45) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL16212397 | 0.94 | SMN1; SMN2 (0.45) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| SCHEMBL21283424 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| SCHEMBL21882634 | 0.90 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL17560850 | 0.89 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| SCHEMBL21882655 | 0.89 | ALDH1A1 (0.53) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL17560851 | 0.89 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392363-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2019-08-27 | — | — | US | claimed |
| EP-3188722-B1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-08-04 | — | — | EP | disclosed |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | ALDH1A1 840/4885KDM4E 3521/4885POLB 3872/4885 |
| US-10392363-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | ALDH1A1 840/4885KDM4E 3521/4885POLB 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.