SCHEMBL194520

SCHEMBL194520

O=C(OC[C](O)O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.63
ALDH1A1 P00352 3/20 0.61
L3MBTL1 Q9Y468 3/20 0.61
KDM4E B2RXH2 2/20 0.61
GAA P10253 2/20 0.61
KMT2A Q03164 2/20 0.61
MAPK1 P28482 1/20 0.61
HIF1A Q16665 1/20 0.61
SLC6A2 P23975 1/20 0.61
SLC6A3 Q01959 1/20 0.61
RAB9A P51151 3/20 0.59
NPC1 O15118 2/20 0.59
HPGD P15428 2/20 0.59
LMNA P02545 2/20 0.59
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
F2 P00734 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
NFKB1 P19838 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL582352 0.86 TDP1 (0.63) TDP1ALDH1A1L3MBTL1KDM4EGAA
SCHEMBL4586692 0.86 TDP1 (0.63) TDP1ALDH1A1L3MBTL1KDM4EGAA
SCHEMBL28819015 0.84 TDP1 (0.61) TDP1ALDH1A1L3MBTL1KDM4EGAA
Potassium SCHEMBL31360984 0.84 TDP1 (0.61) TDP1ALDH1A1L3MBTL1KDM4EGAA
SCHEMBL83331 0.84 RAB9A (0.79) TDP1ALDH1A1L3MBTL1KDM4EGAA
SCHEMBL27502116 0.84 TDP1 (0.61) TDP1ALDH1A1L3MBTL1KDM4EGAA
SCHEMBL4655187 0.83 TDP1 (0.59) TDP1ALDH1A1L3MBTL1KDM4EGAA
SCHEMBL11063346 0.83 TSHR (0.61) TDP1ALDH1A1L3MBTL1KDM4EGAA
SCHEMBL714886 0.83 RAB9A (0.61) TDP1ALDH1A1L3MBTL1KDM4EGAA
SCHEMBL14457923 0.83 TDP1 (0.59) TDP1ALDH1A1L3MBTL1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
EP-3019473-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2020-02-19 EP disclosed
US-10488756-B2 Oxime ester photoinitiators BASF SE (DE) 2019-11-26 US disclosed
EP-3354641-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-07-17 EP disclosed
US-10234761-B2 Oxime ester photoinitiators BASF SE (DE) 2019-03-19 US disclosed
EP-2847167-B9 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-02-20 EP disclosed
EP-3354641-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-08-01 EP disclosed
EP-2847167-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-07-18 EP disclosed
EP-1794240-A1 USE OF PYRIMIDO[5,4-G]PTERIDINES AS SHADING COMPONENT IN COLOR FILTER COLORANT COMPOSITIONS Ciba Specialty Chemicals Holding Inc. (CH) 2007-06-13 EP disclosed
US-7189489-B2 Oxime ester photoiniators having a combined structure CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-03-13 US disclosed
WO-2006037728-A1 USE OF PYRIMIDO[5,4-G]PTERIDINES AS SHADING COMPONENT IN COLOR FILTER COLORANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-04-13 WO disclosed
US-6949678-B2 Oxime ester photoinitiators CIBA SPECIALTY CHEMICALS CORP. (US) 2005-09-27 US disclosed
US-20050191567-A1 Oxime ester photoinitiators KUNIMOTO KAZUHIKO (JP) 2005-09-01 US disclosed
US-20040170924-A1 Oxime ester photoiniators having a combined structure CIBA CORPORATION 2004-09-02 US disclosed
US-6596445-B1 Initiators for photopolymerization of radically polymerizable compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 US disclosed
US-20020020832-A1 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORP. 2002-02-21 US disclosed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 US disclosed
US-5663212-A Light-sensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TDP1 3327/4885ALDH1A1 823/4885L3MBTL1 1060/4885
US-10488756-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TDP1 3327/4885ALDH1A1 823/4885L3MBTL1 1060/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TDP1 3339/4885ALDH1A1 779/4885L3MBTL1 1093/4885
US-10234761-B2 Oxime ester photoinitiators C9, C5, CBR3 TDP1 3900/4885ALDH1A1 2225/4885L3MBTL1 660/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TDP1 3327/4885ALDH1A1 823/4885L3MBTL1 1060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.