SCHEMBL714886

SCHEMBL714886

CC(=O)COC(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.61
NPC1 O15118 2/20 0.61
LMNA P02545 2/20 0.60
TDP1 Q9NUW8 2/20 0.59
ALDH1A1 P00352 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
KDM4E B2RXH2 2/20 0.58
GAA P10253 2/20 0.58
KMT2A Q03164 3/20 0.57
MAPK1 P28482 1/20 0.57
HIF1A Q16665 1/20 0.57
SLC6A2 P23975 1/20 0.57
SLC6A3 Q01959 1/20 0.57
TSHR P16473 2/20 0.56
HPGD P15428 2/20 0.56
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.53
NFKB1 P19838 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL28746438 0.94 RAB9A (0.56) RAB9ANPC1LMNATDP1ALDH1A1
SCHEMBL11063346 0.88 TSHR (0.61) RAB9ANPC1LMNATDP1ALDH1A1
SCHEMBL6354305 0.84 RAB9A (0.57) RAB9ANPC1LMNATDP1ALDH1A1
SCHEMBL6502006 0.84 RAB9A (0.57) RAB9ANPC1LMNATDP1ALDH1A1
SCHEMBL31344419 0.84 RAB9A (0.57) RAB9ANPC1LMNATDP1ALDH1A1
SCHEMBL4586692 0.83 TDP1 (0.63) RAB9ANPC1LMNATDP1ALDH1A1
SCHEMBL582352 0.83 TDP1 (0.63) RAB9ANPC1LMNATDP1ALDH1A1
SCHEMBL194520 0.83 TDP1 (0.63) RAB9ANPC1LMNATDP1ALDH1A1
Anthracene SCHEMBL28077695 0.82 MEN1 (0.47) RAB9ANPC1TDP1KDM4EKMT2A
SCHEMBL24112404 0.82 RAB9A (0.64) RAB9ANPC1LMNATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104419326-A Slurry composition for chemical mechanical polishing COWON INNOTECH INC 2015-03-18 CN claimed
CN-119827695-A Degradation impurity detection method of teprenone capsules 浙江核力欣健药业有限公司 2025-04-15 CN disclosed
US-20230212152-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2023-07-06 US disclosed
CN-113214164-B Synthetic method of intermediate 2,4-dimethylpyrimidin-5-ol of Lebo Lei Sheng 广西天铭药业有限公司 2022-10-18 CN disclosed
WO-2021252644-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2021-12-16 WO disclosed
CN-113214164-A Synthetic method of Leborane intermediate 2, 4-dimethylpyrimidine-5-ol 广西天铭药业有限公司 2021-08-06 CN disclosed
CN-110337308-A exon skipping oligomer conjugates for muscular dystrophy 萨勒普塔医疗公司 2019-10-15 CN disclosed
CN-110290812-A exon skipping oligomer conjugates for muscular dystrophy 萨勒普塔医疗公司 2019-09-27 CN disclosed
CN-109563114-A Process for preparing oligomers 萨勒普塔医疗公司 2019-04-02 CN disclosed
US-9512115-B2 Inhibitors PROBIODRUG AG (DE) 2016-12-06 US disclosed
US-20070015782-A1 Benzimidazole compound EISAI CO., LTD. 2007-01-18 US disclosed
US-20070015782-A1 Benzimidazole compound EISAI CO., LTD. 2007-01-18 US disclosed
US-20070015782-A1 Benzimidazole compound EISAI CO., LTD. 2007-01-18 US disclosed
US-20070010542-A1 Benzimidazole compound EISAI CO., LTD. 2007-01-11 US disclosed
US-20070010542-A1 Benzimidazole compound EISAI CO., LTD. 2007-01-11 US disclosed
US-20070010542-A1 Benzimidazole compound EISAI CO., LTD. 2007-01-11 US disclosed
CN-1038930-C Azetidinone derivatives useful in preparation of carbapenem antibiotics SANKYO CO (JP) 1998-07-01 CN disclosed
EP-0646002-A1 PREPARATION AND USE OF NOVEL CYCLODEXTRIN-BASED DISPERSIBLE NANOVESICULAR COLLOIDAL SYSTEMS IN THE FORM OF NANOCAPSULES. CENTRE NAT RECH SCIENT (FR) 1995-04-05 EP disclosed
WO-1993025194-A1 PREPARATION AND USE OF NOVEL CYCLODEXTRIN-BASED DISPERSIBLE NANOVESICULAR COLLOIDAL SYSTEMS IN THE FORM OF NANOCAPSULES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1993-12-23 WO disclosed
CN-1068108-A Be used to prepare the aza cyclo-butanone derivatives of carbapenem antibiotics SANKYO CO (JP) 1993-01-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010542-A1 Benzimidazole compound HRH2, GIPR, HRH4 RAB9A 1686/4885NPC1 1355/4885LMNA 3526/4885
US-20070015782-A1 Benzimidazole compound HRH2, GIPR, HRH4 RAB9A 1686/4885NPC1 1355/4885LMNA 3526/4885
US-20230212152-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTRL, CTSL, CTSV RAB9A 2344/4885NPC1 481/4885LMNA 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.