Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849443 | 0.90 | POLB (0.43) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4630156 | 0.77 | TSHR (0.40) | BRPF1ACACBTSHRGABRPGABRD | |
| SCHEMBL16036865 | 0.75 | CHRNB2 (0.56) | BRPF1ACACBKDM5ATSHRGABRP | |
| SCHEMBL12696525 | 0.75 | CHRNB2 (0.56) | BRPF1ACACBKDM5ATSHRGABRP | |
| Hydrochloric Acid SCHEMBL2146410 | 0.74 | CHRNB2 (0.54) | BRPF1ACACBKDM5ATSHRGABRP | |
| Hydrochloric Acid SCHEMBL2146404 | 0.74 | CHRNB2 (0.54) | BRPF1ACACBKDM5ATSHRGABRP | |
| SCHEMBL13282077 | 0.73 | ATM (0.40) | KDM4EATMCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL23658084 | 0.72 | GABRA5 (0.43) | BRPF1TSHRGABRPGABRDGABRA1 | |
| SCHEMBL15082262 | 0.72 | — | — | |
| SCHEMBL20368646 | 0.72 | GABRA5 (0.43) | BRPF1TSHRGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017175068-A1 | THIAZOLOPYRIDINE DERIVATIVES AS GPR119 AGONISTS | MANKIND PHARMA LTD. (IN) | 2017-10-12 | — | — | WO | disclosed |