Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002821 | 0.80 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2RAB9AMAPTLMNA | |
| SCHEMBL19454935 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EALOX15HSD17B10HDAC6 | |
| SCHEMBL568378 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EALOX15HSD17B10HDAC1 | |
| SCHEMBL30299648 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL3121440 | 0.73 | KDM4E (0.46) | ALDH1A1KDM4EALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL568288 | 0.72 | KDM4E (0.36) | ALDH1A1KDM4EALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL13002831 | 0.68 | ALDH1A1 (0.61) | ALDH1A1KDM4EALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL13002824 | 0.68 | L3MBTL1 (0.41) | ALDH1A1KDM4EHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL3772652 | 0.67 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2RAB9AMAPTLMNA | |
| SCHEMBL13752168 | 0.67 | POLB (0.43) | ALDH1A1KDM4EHSD17B10SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017175068-A1 | THIAZOLOPYRIDINE DERIVATIVES AS GPR119 AGONISTS | MANKIND PHARMA LTD. (IN) | 2017-10-12 | — | — | WO | disclosed |