Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.52 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.52 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL17926315 | 1.00 | HTT (0.55) | HTTLMNARAD52HSP90AA1SMN1; SMN2 | |
| Bromide SCHEMBL29987617 | 1.00 | HTT (0.55) | HTTLMNARAD52HSP90AA1SMN1; SMN2 | |
| Bromide SCHEMBL17926316 | 0.98 | HTT (0.53) | HTTLMNARAD52HSP90AA1SMN1; SMN2 | |
| SCHEMBL296028 | 0.98 | HTT (0.57) | HTTLMNARAD52CHRM2ADRA2A | |
| SCHEMBL29394041 | 0.98 | HTT (0.57) | HTTLMNARAD52CHRM2ADRA2A | |
| Hydrochloric Acid SCHEMBL17926382 | 0.96 | HTT (0.55) | HTTLMNARAD52HSP90AA1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29465194 | 0.96 | HTT (0.55) | HTTLMNARAD52HSP90AA1SMN1; SMN2 | |
| Iodide SCHEMBL16107451 | 0.96 | HTT (0.55) | HTTLMNARAD52SMN1; SMN2CHRM2 | |
| Fluoride Ion SCHEMBL30213090 | 0.96 | HTT (0.55) | HTTLMNARAD52CHRM2ADRA2A | |
| Water SCHEMBL15375382 | 0.96 | HTT (0.55) | HTTLMNARAD52CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976234-B1 | QUATERNARY AMMONIUM HALIDES FOR TREATING HALOGEN CONTAMINATION | BROMINE COMPOUNDS LTD (IL) | 2026-05-27 | — | — | EP | claimed |
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | UNIV MURCIA (ES) | 2026-03-19 | — | — | US | claimed |
| CN-117126654-B | Blocking remover, preparation method, use method and application | 中国石油天然气股份有限公司 | 2025-05-23 | — | — | CN | claimed |
| EP-4556514-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | Universidad de Murcia (ES) | 2025-05-21 | — | — | EP | claimed |
| CN-114566723-B | Electrolyte for rechargeable electrochemical cells | EOS能源技术控股有限责任公司 | 2025-03-04 | — | — | CN | claimed |
| US-20240342530-A1 | QUARTERNARY AMMONIUM HALIDES FOR TREATING HALOGEN CONTAMINATION | BROMINE COMPOUNDS LTD (IL) | 2024-10-17 | — | — | US | claimed |
| CN-117839636-B | Treatment agent and treatment method for eutrophic cultivation wastewater | 金满塘(天津)生物科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117839636-A | Treatment agent and treatment method for eutrophic cultivation wastewater | 金满塘(天津)生物科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-114007703-B | Quaternary ammonium halides for treating halogen pollution | 溴化合物有限公司 | 2024-03-22 | — | — | CN | claimed |
| EP-4315482-A1 | HALOGEN COMPLEXING AGENTS BOUND TO THE CATHODE SURFACE IN A STATIC ZINC HALIDE BATTERY | EOS Energy Technology Holdings, LLC (US) | 2024-02-07 | — | — | EP | claimed |
| CN-105026371-A | Process for preparing 1-alkyl-3-alkyl-pyridinium bromides and their use as additives in electrochemical cells | BROMINE COMPOUNDS LTD | 2015-11-04 | — | — | CN | claimed |
| EP-2934469-A2 | ORAL CARE COMPOSITION CONTAINING IONIC LIQUIDS | Colgate-Palmolive Company (US) | 2015-10-28 | — | — | EP | claimed |
| WO-2015125095-A1 | PROCESS FOR OXIDATION OF ALKYL AROMATIC COMPOUND TO AROMATIC CARBOXYLIC ACID | RELIANCE INDUSTRIES LIMITED (IN) | 2015-08-27 | — | — | WO | claimed |
| WO-2014122641-A1 | PROCESSES FOR PREPARING L-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | BROMINE COMPOUNDS LTD. (IL) | 2014-08-14 | — | — | WO | claimed |
| WO-2014098871-A2 | ORAL CARE COMPOSITION CONTAINING IONIC LIQUIDS | COLGATE-PALMOLIVE COMPANY (US) | 2014-06-26 | — | — | WO | claimed |
| EP-2195295-B1 | METHOD FOR THE PREPARATION OF MONTELUKAST ACID IN IONIC LIQUID MEDIUM | HANMI SCIENCE CO LTD (KR) | 2013-01-23 | — | — | EP | claimed |
| US-8217100-B2 | Adhesive composition and optical member | CHEIL INDUSTRIES, INC. (KR) | 2012-07-10 | — | — | US | claimed |
| EP-2195295-A1 | METHOD FOR THE PREPARATION OF MONTELUKAST ACID IN IONIC LIQUID MEDIUM | Hanmi Pharm. Co., Ltd. (KR) | 2010-06-16 | — | — | EP | claimed |
| WO-2009048236-A1 | METHOD FOR THE PREPARATION OF MONTELUKAST ACID IN IONIC LIQUID MEDIUM | HANMI PHARM. CO., LTD. (KR) | 2009-04-16 | — | — | WO | claimed |
| US-20090014123-A1 | Adhesive composition and optical member | Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) | 2009-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | FGB, POLR2B, POLB | CHRM2 3826/4885CHRM4 4538/4885CHRM5 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.