Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296028 | 0.98 | HTT (0.57) | HTTKDM4EAPAF1ALDH1A1LMNA | |
| SCHEMBL29394041 | 0.98 | HTT (0.57) | HTTKDM4EAPAF1ALDH1A1LMNA | |
| Bromide SCHEMBL29987617 | 0.96 | HTT (0.55) | HTTKDM4EAPAF1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL17926382 | 0.96 | HTT (0.55) | HTTKDM4EAPAF1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL29465194 | 0.96 | HTT (0.55) | HTTKDM4EAPAF1ALDH1A1LMNA | |
| Bromide SCHEMBL17926315 | 0.96 | HTT (0.55) | HTTKDM4EAPAF1ALDH1A1LMNA | |
| Iodide SCHEMBL16107451 | 0.96 | HTT (0.55) | HTTKDM4EAPAF1ALDH1A1LMNA | |
| Bromide SCHEMBL194547 | 0.96 | HTT (0.55) | HTTKDM4EAPAF1ALDH1A1LMNA | |
| Fluoride Ion SCHEMBL30213090 | 0.96 | HTT (0.55) | HTTKDM4EAPAF1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL322540 | 0.96 | HTT (0.55) | HTTKDM4EAPAF1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662332-B1 | MANUFACTURING METHOD FOR FLUORINE-CONTAINING SULFONYL IMIDE SALT | NIPPON SODA CO (JP) | 2018-03-28 | — | — | EP | disclosed |
| US-9233849-B2 | Process for producing fluorine-containing sulfonylimide salt | NIPPON SODA CO., LTD. (JP) | 2016-01-12 | — | — | US | disclosed |
| US-20130323155-A1 | PROCESS FOR PRODUCING FLUORINE-CONTAINING SULFONYLIMIDE SALT | NIPPON SODA CO., LTD. (JP) | 2013-12-05 | — | — | US | disclosed |
| EP-2662332-A1 | MANUFACTURING METHOD FOR FLUORINE-CONTAINING SULFONYL IMIDE SALT | Nippon Soda Co., Ltd. (JP) | 2013-11-13 | — | — | EP | disclosed |