Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.34 |
| ▸ | PMM2 | O15305 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418995 | 0.89 | MAPT (0.42) | MAPTTSHRTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL6847622 | 0.85 | TSHR (0.33) | MAPTTSHRTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL13219689 | 0.81 | MAPT (0.40) | MAPTTXNRD1TXNRD3TXNRD2KMT2A | |
| SCHEMBL5708807 | 0.79 | MAPT (0.39) | MAPTTXNRD1TXNRD3TXNRD2KMT2A | |
| SCHEMBL5708847 | 0.79 | TSHR (0.42) | MAPTTSHRTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL12170150 | 0.79 | MAPT (0.39) | MAPTTXNRD1TXNRD3TXNRD2KMT2A | |
| SCHEMBL18217202 | 0.76 | MAPT (0.41) | MAPTTXNRD1TXNRD3TXNRD2KMT2A | |
| SCHEMBL19456668 | 0.66 | TSHR (0.39) | MAPTTSHRALDH1A1 | |
| SCHEMBL5708797 | 0.66 | ALDH1A1 (0.48) | MAPTTSHRTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL5708726 | 0.66 | KMT2A (0.47) | MAPTTSHRTXNRD1TXNRD3TXNRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711138-B2 | Intermediates and procedures for the synthesis of functional materials | MERCK PATENT GMBH (DE) | 2020-07-14 | — | — | US | disclosed |
| US-20190127586-A1 | INTERMEDIATES AND PROCEDURES FOR THE SYNTHESIS OF FUNCTIONAL MATERIALS | MERCK PATENT GMBH (DE) | 2019-05-02 | — | — | US | disclosed |
| WO-2017174619-A1 | INTERMEDIATES AND PROCEDURES FOR THE SYNTHESIS OF FUNCTIONAL MATERIALS | MERCK PATENT GMBH (DE) | 2017-10-12 | — | — | WO | disclosed |