Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.30 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708807 | 0.87 | MAPT (0.39) | MAPTTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL5708847 | 0.87 | TSHR (0.42) | TSHRMAPTTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL19456660 | 0.85 | MAPT (0.36) | TSHRMAPTTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL13219689 | 0.78 | MAPT (0.40) | MAPTTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL2418995 | 0.78 | MAPT (0.42) | TSHRMAPTTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL12170150 | 0.73 | MAPT (0.39) | MAPTTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL18217202 | 0.70 | MAPT (0.41) | MAPTTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL3476651 | 0.65 | TSHR (0.65) | TSHRMAPTTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL3518192 | 0.65 | ALDH1A1 (0.38) | TSHRMAPT | |
| SCHEMBL5708797 | 0.64 | ALDH1A1 (0.48) | TSHRMAPTTXNRD1TXNRD3TXNRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | KRT18, AOC1, S100B | TSHR 2949/4885MAPT 2273/4885TXNRD1 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.