Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533945 | 0.88 | STAT3 (0.49) | STAT3STAT1 | |
| SCHEMBL4429826 | 0.82 | STAT3 (0.45) | STAT3STAT1 | |
| SCHEMBL5585185 | 0.82 | STAT3 (0.45) | STAT3STAT1 | |
| SCHEMBL1944649 | 0.82 | STAT3 (0.45) | STAT3STAT1 | |
| SCHEMBL14867477 | 0.81 | STAT3 (0.49) | STAT3STAT1 | |
| SCHEMBL4551743 | 0.81 | STAT3 (0.44) | STAT3STAT1 | |
| SCHEMBL3527775 | 0.80 | STAT3 (0.43) | STAT3STAT1 | |
| SCHEMBL5133634 | 0.79 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL3527769 | 0.79 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL17419209 | 0.79 | STAT3 (0.51) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136774-A1 | Anti-Apoptotic Benzodiazepine Receptor Ligand Inhibitors | MALFROY-CAMINE BERNARD | 2011-06-09 | — | — | US | disclosed |
| US-20100120738-A1 | ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS | MALFROY-CAMINE BERNARD | 2010-05-13 | — | — | US | disclosed |
| WO-2008033444-A2 | ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS | EUKARION, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120738-A1 | ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS | AIFM1, BAK1, BAX | STAT3 2102/4885STAT1 3428/4885 |
| US-20110136774-A1 | Anti-Apoptotic Benzodiazepine Receptor Ligand Inhibitors | AIFM1, BAK1, BAX | STAT3 2102/4885STAT1 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.