SCHEMBL4551743

SCHEMBL4551743

CCCCCc1c2nc(cc3ccc([nH]3)c(CCCCC)c3nc(cc4ccc1[nH]4)C=C3)C=C2

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.44
▸ STAT1 P42224 1/20 0.44
▸ MAPT P10636 2/20 0.33
▸ HTT P42858 2/20 0.33
▸ SIRT1 Q96EB6 1/20 0.33
▸ HSD17B10 Q99714 3/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ HPGD P15428 2/20 0.32
▸ LMNA P02545 1/20 0.32
▸ XBP1 P17861 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ GPR84 Q9NQS5 3/20 0.32
▸ KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17419215 0.99 STAT3 (0.43) STAT3STAT1MAPTHTTHSD17B10
SCHEMBL5133634 0.97 STAT3 (0.42) STAT3STAT1MAPTHTTSIRT1
SCHEMBL3520094 0.96 STAT3 (0.41) STAT3STAT1MAPTHTTHSD17B10
SCHEMBL15510967 0.96 STAT3 (0.41) STAT3STAT1MAPTHTTHSD17B10
SCHEMBL7647119 0.96 STAT3 (0.41) STAT3STAT1MAPTHTTHSD17B10
SCHEMBL3522373 0.96 STAT3 (0.41) STAT3STAT1MAPTHTTHSD17B10
SCHEMBL6003904 0.96 STAT3 (0.41) STAT3STAT1MAPTHTTHSD17B10
SCHEMBL4944703 0.96 STAT3 (0.40) STAT3STAT1MAPTHTTSIRT1
Hydrochloric Acid SCHEMBL27872840 0.95 STAT3 (0.40) STAT3STAT1MAPTHTTHSD17B10
SCHEMBL29910098 0.95 STAT3 (0.39) STAT3STAT1MAPTHTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1193793-C Diarylprophin photosensitizer and its preparing process and usage CHINESE ACAD INST CHEMISTRY (CN) 2005-03-23 — — CN claimed
CN-1382493-A Diarylprophin photosensitizer and its preparing process and usage INST OF CHEMICSTRY CHINESE ACA (CN) 2002-12-04 — — CN claimed
CN-118267472-A Naphthopin cation derivative and application thereof in biological medicine and material field 上海先辉医药科技有限公司 2024-07-02 — — CN disclosed
EP-3419977-B1 PLATINUM(II) RING-FUSED CHLORINS, METHODS AND USES THEREOF UNIV DE COIMBRA (PT) 2024-01-03 — — EP disclosed
US-10493168-B2 Phosphorescent meso-unsubstituted metallo-porphyrin probe molecules for measuring oxygen and imaging methods OXYGEN ENTERPRISES, LTD (US) 2019-12-03 — — US disclosed
EP-3419977-A1 PLATINUM(II) RING-FUSED CHLORINS, METHODS AND USES THEREOF Universidade de Coimbra (PT) 2019-01-02 — — EP disclosed
CN-105315699-B Zinc purple photosensitive dye and photoelectric conversion device thereof 财团法人工业技术研究院 2018-04-13 — — CN disclosed
WO-2017145092-A1 PLATINUM(II) RING-FUSED CHLORINS, METHODS AND USES THEREOF UNIVERSIDADE DE COIMBRA (PT) 2017-08-31 — — WO disclosed
US-20170137449-A1 Phosphorescent Meso-Unsubstituted Metallo-Porphyrin Probe Molecules for Measuring Oxygen and Imaging Methods OXYPHOR, LLC 2017-05-18 — — US disclosed
US-9556213-B2 Phosphorescent meso-unsubstituted metallo-tetrabenzoporphyrin probe molecules for measuring oxygen and imaging methods OXYGEN ENTERPRISES, LTD 2017-01-31 — — US disclosed
US-9546278-B2 Porphyrin photosensitive dye and photoelectric conversion device utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-01-17 — — US disclosed
US-5990363-A Method for oxidizing alkanes using novel porphyrins synthesized from dipyrromethanes and aldehydes SUN COMPANY, INC. (US) 1999-11-23 — — US disclosed
US-5780622-A CYCLIZATION, OXIDATION THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1998-07-14 — — US disclosed
US-5760217-A Porphyrins and their synthesis from dipyrromethanes and aldehydes SUN COMPANY, INC. (US) 1998-06-02 — — US disclosed
US-5723677-A Method for hydroperoxide decomposition using novel porphyrins synthesized from dipyrromethanes and aldehydes SUN COMPANY, INC. (R&M) (US) 1998-03-03 — — US disclosed
US-5656756-A PHOTOSENSITIZERS IN PHOTODYNAMIC THERAPY, ANTITUMOR AGENTS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1997-08-12 — — US disclosed
US-5571908-A Porphyrins SUN COMPANY, INC. (R&M) (US) 1996-11-05 — — US disclosed
WO-1995029914-A1 A METHOD OF SYNTHESIZING 5,15-DIARYLBENZOCHLORIN-7-ONE COMPOUNDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1995-11-09 — — WO disclosed
EP-0665056-A2 Method for oxidizing alkanes using halocarbyl-substituted porphyrins synthesized from meso-halocarbyl-dipyrromethanes and aldehydes SUN COMPANY, INC. (R&M) (US) 1995-08-02 — — EP disclosed
EP-0665230-A2 Halocarbyl-substituted porphyrins and their synthesis from meso-halocarbyl-dipyrromethanes and aldehydes SUN COMPANY, INC. (R&M) (US) 1995-08-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137449-A1 Phosphorescent Meso-Unsubstituted Metallo-Porphyrin Probe Molecules for Measuring Oxygen and Imaging Methods PPOX, PLPBP, DUOX2 STAT3 707/4885STAT1 955/4885MAPT 1198/4885
US-10493168-B2 Phosphorescent meso-unsubstituted metallo-porphyrin probe molecules for measuring oxygen and imaging methods PPOX, PLPBP, DUOX2 STAT3 707/4885STAT1 955/4885MAPT 1198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback