SCHEMBL19463306

SCHEMBL19463306

C[C@]1(CO)CNC[C@@]1(C)CO

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
GAA P10253 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23560959 1.00 EPHX1 (0.33) EPHX1GAA
SCHEMBL24469076 0.76
SCHEMBL15276076 0.75
Hydrochloric Acid SCHEMBL15262766 0.73
SCHEMBL25533598 0.71 HSD17B10 (0.31)
SCHEMBL8521872 0.67
SCHEMBL1443719 0.66 EPHX1 (0.37) EPHX1
SCHEMBL75645 0.65
SCHEMBL24317044 0.65
Hydrochloric Acid SCHEMBL3580219 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179496-A1 TARGETED COMPOSITIONS ARBUTUS BIOPHARMA CORPORATION (US) 2025-06-05 US disclosed
CN-113226332-B Bivalent targeting conjugates 阿布特斯生物制药公司 2025-05-09 CN disclosed
US-20250099594-A1 TARGETED COMPOSITIONS ARBUTUS BIOPHARMA CORPORATION (US) 2025-03-27 US disclosed
CN-118460536-A Targeting composition 阿布特斯生物制药公司 2024-08-09 CN disclosed
US-20240245784-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS ARBUTUS BIOPHARMA CORPORATION (US) 2024-07-25 US disclosed
US-12043833-B2 Targeted compositions ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-23 US disclosed
US-12043833-B2 Targeted compositions ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-23 US disclosed
US-12043833-B2 Targeted compositions ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-23 US disclosed
CN-110741087-B Targeting composition 阿布特斯生物制药公司 2024-05-14 CN disclosed
US-11896672-B2 Targeted nucleic acid conjugate compositions ARBUTUS BIOPHARMA CORPORATION (CA) 2024-02-13 US disclosed
US-20200407724-A1 TARGETED COMPOSITIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2020-12-31 US disclosed
EP-3610017-A2 TARGETED COMPOSITIONS Arbutus Biopharma Corporation (CA) 2020-02-19 EP disclosed
US-20190160176-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2019-05-30 US disclosed
US-20190160176-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2019-05-30 US disclosed
WO-2019051257-A2 METHODS FOR TREATING HEPATITIS B INFECTIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2019-03-14 WO disclosed
WO-2019051257-A2 METHODS FOR TREATING HEPATITIS B INFECTIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2019-03-14 WO disclosed
EP-3443092-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS Arbutus Biopharma Corporation (CA) 2019-02-20 EP disclosed
WO-2018191278-A2 TARGETED COMPOSITIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2018-10-18 WO disclosed
WO-2017177326-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS PROTIVA BIOTHERAPEUTICS, INC. (CA) 2017-10-19 WO disclosed
WO-2017177326-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS PROTIVA BIOTHERAPEUTICS, INC. (CA) 2017-10-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190160176-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS HAVCR2, DCTD, POLRMT EPHX1 1919/4885GAA 514/4885
US-20250099594-A1 TARGETED COMPOSITIONS HAVCR2, HDGF, NR1H4 EPHX1 1220/4885GAA 479/4885
US-11896672-B2 Targeted nucleic acid conjugate compositions HAVCR2, DCTD, POLRMT EPHX1 1919/4885GAA 514/4885
US-20240245784-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS HAVCR2, DCTD, POLRMT EPHX1 1919/4885GAA 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.