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Sugi Predict / Compounds / Prosulfuron

Prosulfuron

Prosulfuron

SCHEMBL19463550

COc1c(Cl)ccc(Cl)c1C(=O)O.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2CCC(F)(F)F)n1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ KMT2A Q03164 1/20 0.40
▸ MAPT P10636 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ TAS1R3 Q7RTX0 1/20 0.33
▸ TAS1R1 Q7RTX1 1/20 0.33
▸ TAS1R2 Q8TE23 1/20 0.33
▸ GAA P10253 1/20 0.31
▸ FBP1 P09467 1/20 0.31
▸ TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prosulfuron SCHEMBL19463753 0.89 ALDH1A1 (0.42) ALDH1A1KDM4ENPC1KMT2AMAPT
Prosulfuron SCHEMBL29440211 0.89 MAPT (0.44) ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Prosulfuron SCHEMBL56036 0.89 MAPT (0.44) ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Prosulfuron SCHEMBL30298017 0.89 MAPT (0.44) ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Prosulfuron SCHEMBL7576562 0.84 KDM4E (0.31) ALDH1A1KDM4ENPC1
Prosulfuron SCHEMBL7575579 0.84 PPOX (0.46) ALDH1A1KDM4ENPC1
SCHEMBL9242425 0.84 MAPT (0.44) ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
SCHEMBL10383749 0.83 MAPT (0.46) ALDH1A1KDM4ENPC1MAPTSMN1; SMN2
Prosulfuron SCHEMBL7577548 0.83 TDP1 (0.46) KMT2AMAPTSMN1; SMN2
Prosulfuron SCHEMBL7585678 0.83 TDP1 (0.44) ALDH1A1KDM4ENPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442962-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS Syngenta Participations AG (CH) 2019-02-20 — — EP disclosed
WO-2017178582-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2017-10-19 — — WO disclosed