Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464501 | 0.87 | TGM2 (0.47) | TGM2NAPRTHSD17B10POLBMAPT | |
| SCHEMBL21282687 | 0.85 | TGM2 (0.42) | TGM2NAPRTHSD17B10POLBMAPT | |
| SCHEMBL21844942 | 0.83 | TGM2 (0.55) | TGM2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL18773971 | 0.83 | MEN1 (0.48) | MAPTKMT2AKDM4EMEN1HPGD | |
| SCHEMBL20404365 | 0.80 | TGM2 (0.44) | TGM2NAPRTHSD17B10POLBMAPT | |
| SCHEMBL19720082 | 0.79 | TGM2 (0.46) | TGM2NAPRTHSD17B10POLBMAPT | |
| SCHEMBL22757127 | 0.79 | MAPT (0.47) | HSD17B10POLBMAPTKMT2AKDM4E | |
| SCHEMBL25863802 | 0.77 | NPC1 (0.47) | POLBMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL21704669 | 0.76 | RAB9A (0.42) | TGM2NAPRTHSD17B10POLBMAPT | |
| SCHEMBL26355328 | 0.76 | TGM2 (0.50) | TGM2NAPRTHSD17B10POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190255182-A1 | CTB-PI POLYAMIDE CONJUGATE FOR ACTIVATING EXPRESSION OF SPECIFIC GENE | KYOTO UNIVERSITY (JP) | 2019-08-22 | — | — | US | disclosed |
| US-9790218-B2 | Small molecule activators of calcium-activated chloride channels and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190255182-A1 | CTB-PI POLYAMIDE CONJUGATE FOR ACTIVATING EXPRESSION OF SPECIFIC GENE | KAT2A, KAT6B, CTBP2 | TGM2 1520/4885NAPRT 461/4885HSD17B10 1566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.