Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127782 | 0.80 | KDM4E (0.52) | KDM4EPAX8PARP1ALDH1A1HPGD | |
| SCHEMBL27765373 | 0.80 | NR1H2 (0.47) | PARP1 | |
| SCHEMBL10705519 | 0.79 | KDM4E (0.59) | KDM4EPAX8TSHRMMP2CHRM1 | |
| SCHEMBL4463430 | 0.79 | KDM4E (0.62) | KDM4EPAX8PARP1TSHRALOX12 | |
| SCHEMBL15547652 | 0.79 | KDM4E (0.49) | KDM4EPAX8PARP1HIF1AHSD17B10 | |
| SCHEMBL12272812 | 0.79 | KDM4E (0.49) | KDM4EPAX8PARP1HIF1AHSD17B10 | |
| SCHEMBL3432556 | 0.78 | KDM4E (0.52) | KDM4ETSHRLMNAALOX12MMP2 | |
| Hydrochloric Acid SCHEMBL9814926 | 0.78 | KDM4E (0.60) | KDM4EPAX8PARP1TSHRALOX12 | |
| Hydrochloric Acid SCHEMBL9814936 | 0.78 | KDM4E (0.60) | KDM4EPAX8PARP1TSHRALOX12 | |
| Oxyquinoline SCHEMBL17889764 | 0.77 | ALDH1A1 (0.64) | KDM4EPAX8TSHRLMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639336-A | RADIOIMMUNOASSAY | ROUSSEL UCLAF (FR) | 1987-01-27 | — | — | US | claimed |
| EP-0131491-A1 | Estradiene derivatives labelled with iodine, process for their preparation and intermediates in their preparation, and their use in the study and the radioimmunological determination of steroids in body fluids | ROUSSEL-UCLAF (FR) | 1985-01-16 | — | — | EP | claimed |
| EP-0114011-A1 | Iodine-labelled radioactive estratriene derivatives, process and intermediates for their preparation, their use in radioimmuno assays and in the preparation of antigens, and antigens so obtained | ROUSSEL-UCLAF (FR) | 1984-07-25 | — | — | EP | claimed |
| US-20110136259-A1 | IMMUNOASSAY FOR CROSS-REACTING SUBSTANCES | Life Technologies Corporation (US) | 2011-06-09 | — | — | US | disclosed |
| US-20090005267-A1 | IMMUNOASSAY FOR CROSS-REACTING SUBSTANCES | INVITROGEN CORPORATION (US) | 2009-01-01 | — | — | US | disclosed |
| WO-2008106653-A1 | IMMUNOASSAY FOR CROSS-REACTING SUBSTANCES | INVITROGEN CORPORATION (US) | 2008-09-04 | — | — | WO | disclosed |
| EP-0361817-B1 | Nucleophilic polysubstituted aryl acridinium esters, conjugates, production and uses thereof | BAYER AG (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6080591-A | USEFUL IN BIOLOGICAL ASSAYS FOR DETERMINATION OF VITAMIN B12, FOLATE, CORTISOL, ESTRADIOL, AND THROMBOXANE B2 | BAYER CORPORATION (US) | 2000-06-27 | — | — | US | disclosed |
| US-5663074-A | INCUBATION OF FOLATE WITH AMINE REACTIVE COMPOUND, ACTIVATION AND INCUBATION THE ACRIDINIUM ESTER-FOLATE CONJUGATE | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5596004-A | SEMEN PRODUCTION | ELI LILLY AND COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5538901-A | ANALYSIS | CIBA CORNING DIAGNOSTICS CORP. (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0661270-A1 | Nucleophilic polysubstituted aryl acridinium esters, conjugates, production and uses thereof | Ciba Corning Diagnostics Corp. (US) | 1995-07-05 | — | — | EP | disclosed |
| EP-0659424-A1 | 2-Phenyl-3-azoylbenzothiophenes for treating male infertility | ELI LILLY AND COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
| US-5241070-A | Biological analysis | CIBA CORNING DIAGNOSTICS CORP. (US) | 1993-08-31 | — | — | US | disclosed |
| US-4639336-A | RADIOIMMUNOASSAY | ROUSSEL UCLAF (FR) | 1987-01-27 | — | — | US | disclosed |
| EP-0131491-A1 | Estradiene derivatives labelled with iodine, process for their preparation and intermediates in their preparation, and their use in the study and the radioimmunological determination of steroids in body fluids | ROUSSEL-UCLAF (FR) | 1985-01-16 | — | — | EP | disclosed |