Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | METAP2 | P50579 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9814926 | 0.98 | KDM4E (0.60) | KDM4EPARP1METAP2MMP2CHRM1 | |
| Hydrochloric Acid SCHEMBL9814936 | 0.98 | KDM4E (0.60) | KDM4EPARP1METAP2MMP2CHRM1 | |
| Nitric Acid SCHEMBL9308497 | 0.90 | PARP1 (0.56) | KDM4EPARP1METAP2MMP2CHRM1 | |
| SCHEMBL7589324 | 0.82 | KDM4E (0.57) | KDM4EPARP1METAP2MMP2CHRM1 | |
| SCHEMBL21651065 | 0.82 | KDM4E (0.57) | KDM4EPARP1METAP2MMP2CHRM1 | |
| SCHEMBL7043349 | 0.82 | KDM4E (0.53) | KDM4EPARP1CHRM1ACHE | |
| Bromide SCHEMBL7469974 | 0.81 | KDM4E (0.55) | KDM4EPARP1METAP2MMP2CHRM1 | |
| SCHEMBL5094347 | 0.81 | PARP1 (0.59) | KDM4EPARP1MEN1KMT2ACYP1A2 | |
| SCHEMBL6171961 | 0.81 | PARP1 (0.59) | KDM4EPARP1HDAC8CYP1A2CYP2A6 | |
| SCHEMBL10705519 | 0.80 | KDM4E (0.59) | KDM4EMETAP2MMP2CHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116851037-A | Preparation method and application of hydroxyquinoline coordinated catalyst and compound | 上海元革新材料科技有限公司 | 2023-10-10 | — | — | CN | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| US-5614635-A | Method for the preparation of pyridine-2,3-dicarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1997-03-25 | — | — | US | claimed |
| EP-0331899-B1 | A method for the sequential oxidation of substituted-8-hydroxy-quinolines to produce substituted-pyridine-2,3-dicarboxylic acids | AMERICAN CYANAMID CO (US) | 1994-04-27 | — | — | EP | claimed |
| EP-0259687-B1 | METHOD FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | claimed |
| EP-0331899-A2 | A method for the sequential oxidation of substituted-8-hydroxy-quinolines to produce substituted-pyridine-2,3-dicarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1989-09-13 | — | — | EP | claimed |
| US-4816588-A | OXIDATION OF 8-SUBSTITUTED QUINOLINES | AMERICAN CYANAMID COMPANY (US) | 1989-03-28 | — | — | US | claimed |
| CN-116851037-A | Preparation method and application of hydroxyquinoline coordinated catalyst and compound | 上海元革新材料科技有限公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-3847889-A1 | BIOCIDAL COMPOSITIONS COMPRISING IRON CHELATORS | Arch Chemicals, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |
| US-20200170249-A1 | Biocidal Compositions Comprising Iron Chelators | ARCH CHEMICALS, INC. | 2020-06-04 | — | — | US | disclosed |
| US-10433548-B2 | Biocidal compositions comprising iron chelators | ARCH CHEMICALS, INC. (US) | 2019-10-08 | — | — | US | disclosed |
| EP-2906038-A1 | BIOCIDAL COMPOSITIONS COMPRISING IRON CHELATORS | Arch Chemicals, Inc. (US) | 2015-08-19 | — | — | EP | disclosed |
| US-20140154189-A1 | Biocidal Compositions Comprising Iron Chelators | ARCH CHEMICALS, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-5284955-A | Herbicide intermediates | AMERICAN CYANAMID COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| US-5122608-A | Hydrolysis ofa 2,3-pyridine- or quinolinedicarboxylic acid diester with water and a acid having an ionization constant of 3; treating with a base and separating | AMERICAN CYANAMID COMPANY (US) | 1992-06-16 | — | — | US | disclosed |
| EP-0259687-B1 | METHOD FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |
| EP-0331899-A2 | A method for the sequential oxidation of substituted-8-hydroxy-quinolines to produce substituted-pyridine-2,3-dicarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1989-09-13 | — | — | EP | disclosed |
| US-4816588-A | OXIDATION OF 8-SUBSTITUTED QUINOLINES | AMERICAN CYANAMID COMPANY (US) | 1989-03-28 | — | — | US | disclosed |
| US-4738796-A | HEAT STABILIZATION USING MIXTURE OF 8-HYDROXYQUINOLINE AND ORGANIC PHOSPHATES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-04-19 | — | — | US | disclosed |
| EP-0259687-A2 | Method for the preparation of pyridine-2,3-dicarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1988-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10433548-B2 | Biocidal compositions comprising iron chelators | SLC40A1, TFRC, SLC39A14 | KDM4E 3199/4885PARP1 2586/4885METAP2 377/4885 |
| US-20140154189-A1 | Biocidal Compositions Comprising Iron Chelators | SLC40A1, TFRC, SLC39A14 | KDM4E 3199/4885PARP1 2586/4885METAP2 377/4885 |
| US-20200170249-A1 | Biocidal Compositions Comprising Iron Chelators | SLC40A1, TFRC, SLC39A14 | KDM4E 3199/4885PARP1 2586/4885METAP2 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.