Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12272812 | 1.00 | KDM4E (0.49) | KDM4ESLC7A5PTGS1HSD17B10USP2 | |
| SCHEMBL8208523 | 0.79 | TPH1 (0.62) | KDM4ESLC7A5PTGS1HSD17B10USP2 | |
| SCHEMBL31614353 | 0.79 | TPH1 (0.62) | KDM4ESLC7A5PTGS1HSD17B10USP2 | |
| SCHEMBL30969128 | 0.79 | TPH1 (0.62) | KDM4ESLC7A5PTGS1HSD17B10USP2 | |
| SCHEMBL287095 | 0.79 | TPH1 (0.62) | KDM4ESLC7A5PTGS1HSD17B10USP2 | |
| SCHEMBL287073 | 0.79 | TPH1 (0.62) | KDM4ESLC7A5PTGS1HSD17B10USP2 | |
| SCHEMBL1946459 | 0.79 | KDM4E (0.54) | KDM4EHSD17B10HIF1ATDP1PAX8 | |
| SCHEMBL8884067 | 0.74 | SLC7A5 (0.54) | KDM4ESLC7A5PTGS1HSD17B10USP2 | |
| SCHEMBL8884063 | 0.74 | SLC7A5 (0.54) | KDM4ESLC7A5PTGS1HSD17B10USP2 | |
| SCHEMBL10705519 | 0.74 | KDM4E (0.59) | KDM4EPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243472-A1 | MODIFIED HELICASES | OXFORD NANOPORE TECHNOLOGIES PLC (GB) | 2025-07-31 | — | — | US | claimed |
| WO-2024138626-A1 | HELICASE TOPIF 1, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING | 深圳华大生命科学研究院 | 2024-07-04 | — | — | WO | claimed |
| CN-118256603-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-117264925-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-116601297-A | Modified helicase and application thereof | 北京齐碳科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| US-20230212535-A1 | MODIFIED HELICASES | OXFORD NANOPORE TECHNOLOGIES PLC (GB) | 2023-07-06 | — | — | US | claimed |
| EP-4198125-A2 | PIF1-LIKE HELICASE AND USE THEREOF | Qitan Technology Ltd., Beijing (CN) | 2023-06-21 | — | — | EP | claimed |
| US-11525125-B2 | Modified helicases | OXFORD NANOPORE TECHNOLOGIES PLC (GB) | 2022-12-13 | — | — | US | claimed |
| EP-4063382-A9 | PIF1-LIKE HELICASE AND APPLICATION THEREOF | Qitan Technology Ltd., Beijing (CN) | 2022-11-16 | — | — | EP | claimed |
| EP-4063382-A1 | PIF1-LIKE HELICASE AND APPLICATION THEREOF | Qitan Technology Ltd., Beijing (CN) | 2022-09-28 | — | — | EP | claimed |
| US-20210009971-A1 | MODIFIED HELICASES | OXFORD NANOPORE TECHNOLOGIES LTD. (GB) | 2021-01-14 | — | — | US | claimed |
| EP-3575410-A2 | MODIFIED ENZYMES | Oxford Nanopore Technologies Limited (GB) | 2019-12-04 | — | — | EP | claimed |
| US-20180037874-A9 | MODIFIED HELICASES | OXFORD NANOPORE TECHNOLOGIES LTD. (GB) | 2018-02-08 | — | — | US | claimed |
| US-20160257942-A1 | MODIFIED HELICASES | OXFORD NANOPORE TECHNOLOGIES LTD. (GB) | 2016-09-08 | — | — | US | claimed |
| EP-3058088-A2 | MODIFIED ENZYMES | Oxford Nanopore Technologies Limited (GB) | 2016-08-24 | — | — | EP | claimed |
| CN-105899678-A | Modified enzymes | 牛津纳米孔技术公司 | 2016-08-24 | — | — | CN | claimed |
| US-20150191709-A1 | MODIFIED HELICASES | OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) | 2015-07-09 | — | — | US | claimed |
| EP-2875128-A1 | MODIFIED HELICASES | Oxford Nanopore Technologies Limited (GB) | 2015-05-27 | — | — | EP | claimed |
| WO-2015055981-A2 | MODIFIED ENZYMES | OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) | 2015-04-23 | — | — | WO | claimed |
| WO-2014013260-A1 | MODIFIED HELICASES | OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) | 2014-01-23 | — | — | WO | claimed |