Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19465764 | 0.86 | MEN1 (0.38) | POLBALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL19465763 | 0.85 | MEN1 (0.46) | POLBALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL14329988 | 0.82 | MEN1 (0.43) | POLBALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL16085321 | 0.82 | ALDH1A1 (0.61) | POLBALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL28566950 | 0.79 | HEXA (0.57) | POLBALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL15383768 | 0.77 | MEN1 (0.57) | POLBALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL12253435 | 0.77 | MAPT (0.53) | POLBALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL26212216 | 0.77 | MAPT (0.53) | POLBALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL12050439 | 0.77 | MAPT (0.53) | POLBALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL15886144 | 0.76 | CYP1B1 (0.58) | ALDH1A1MEN1KMT2AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9791463-B2 | Methods for the selective detection of alkyne-presenting molecules and related compositions and systems | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2017-10-17 | — | — | US | disclosed |