Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19465763 | 0.86 | MEN1 (0.46) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL19465764 | 0.85 | MEN1 (0.38) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL19465765 | 0.82 | POLB (0.41) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL14329995 | 0.82 | KEAP1 (0.57) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL15383768 | 0.78 | MEN1 (0.57) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL28566950 | 0.78 | HEXA (0.57) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL30003710 | 0.78 | CYP1B1 (0.58) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL15886144 | 0.78 | CYP1B1 (0.58) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL14329987 | 0.76 | KMT2A (0.55) | MEN1KMT2AMAPTRAB9APOLB | |
| SCHEMBL14463546 | 0.74 | SIRT1 (0.61) | MEN1KMT2AMAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212189-B2 | Fluorescent probes for reactive sulfur species | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-15 | — | — | US | disclosed |
| US-9212189-B2 | Fluorescent probes for reactive sulfur species | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-15 | — | — | US | disclosed |
| US-20120329085-A1 | FLUORESCENT PROBES FOR REACTIVE SULFUR SPECIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120329085-A1 | FLUORESCENT PROBES FOR REACTIVE SULFUR SPECIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329085-A1 | FLUORESCENT PROBES FOR REACTIVE SULFUR SPECIES | SQOR, CBS, CTH | MEN1 3197/4885KMT2A 4427/4885MAPT 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.