Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | HEXA | P06865 | 3/20 | 0.36 |
| ▸ | HEXB | P07686 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19465763 | 0.88 | MEN1 (0.46) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL19465765 | 0.86 | POLB (0.41) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL14329988 | 0.85 | MEN1 (0.43) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL28566950 | 0.81 | HEXA (0.57) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL15383768 | 0.79 | MEN1 (0.57) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL15886144 | 0.78 | CYP1B1 (0.58) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL30003710 | 0.78 | CYP1B1 (0.58) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL14463546 | 0.77 | SIRT1 (0.61) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL14329987 | 0.77 | KMT2A (0.55) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL30459062 | 0.76 | CYP1B1 (0.53) | MEN1KMT2AMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9791463-B2 | Methods for the selective detection of alkyne-presenting molecules and related compositions and systems | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2017-10-17 | — | — | US | disclosed |