Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.78 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.69 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | FPR2 | P25090 | 1/20 | 0.59 |
| ▸ | CASR | P41180 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | RORC | P51449 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19472678 | 0.91 | FPR2 (0.69) | CNR1ROCK2ROCK1NPC1RAB9A | |
| SCHEMBL22834261 | 0.87 | CNR1 (1.00) | CNR1ROCK2ROCK1NPC1RAB9A | |
| SCHEMBL15306498 | 0.83 | CNR1 (0.73) | CNR1ROCK2ROCK1NPC1RAB9A | |
| SCHEMBL19472696 | 0.82 | CNR1 (0.76) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL5376426 | 0.82 | CNR1 (0.63) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL19472655 | 0.82 | CNR1 (0.88) | CNR1NPC1RAB9ASMN1; SMN2FPR2 | |
| SCHEMBL19472643 | 0.82 | CNR1 (0.76) | CNR1NPC1RAB9ASMN1; SMN2FPR2 | |
| SCHEMBL15140925 | 0.82 | ROCK2 (1.00) | CNR1ROCK2ROCK1NPC1RAB9A | |
| SCHEMBL4606056 | 0.81 | EPHX1 (0.81) | CNR1ROCK2ROCK1NPC1RAB9A | |
| SCHEMBL13960179 | 0.81 | ROCK2 (0.74) | ROCK2ROCK1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298056-A1 | SMALL MOLECULE INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2017-10-19 | — | — | US | disclosed |
| US-20170298056-A1 | SMALL MOLECULE INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298056-A1 | SMALL MOLECULE INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | CD4, CCR5, CCR1 | CNR1 984/4885ROCK2 608/4885ROCK1 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.