SCHEMBL194741

SCHEMBL194741

C=COC(=O)CCCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.56
HDAC3 O15379 3/20 0.56
HDAC2 Q92769 3/20 0.56
HDAC8 Q9BY41 3/20 0.56
HDAC6 Q9UBN7 3/20 0.56
HDAC5 Q9UQL6 3/20 0.56
HDAC4 P56524 2/20 0.56
HDAC7 Q8WUI4 2/20 0.56
HDAC10 Q969S8 2/20 0.56
HDAC11 Q96DB2 2/20 0.56
HDAC9 Q9UKV0 2/20 0.56
MAPK1 P28482 1/20 0.56
ADRA1A P35348 1/20 0.56
SLC6A3 Q01959 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
TDP1 Q9NUW8 5/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27536338 0.95 HDAC1 (0.51) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL11418333 0.93 MAPT (0.59) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL11119017 0.93 MAPT (0.59) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL19506898 0.91 THRB (0.42) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL347597 0.89 TDP1 (0.61) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL27608422 0.88 HDAC1 (0.58) HDAC1HDAC3HDAC2HDAC8HDAC6
Acetic Acid SCHEMBL27752250 0.85 TDP1 (0.56) HDAC2HDAC8HDAC6TDP1NPC1
SCHEMBL27542082 0.84 TDP1 (0.45) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL19519440 0.83 CYP4Z1 (0.41) HDAC1HDAC3HDAC2HDAC8HDAC6
SCHEMBL11091345 0.83 SMN1; SMN2 (0.56) HDAC1HDAC3HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113316744-B Oxime ester photoinitiators with special aroyl chromophores 巴斯夫欧洲公司 2024-07-30 CN disclosed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
EP-4114825-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-01-11 EP disclosed
US-20220332876-A1 HYDROPHILIC-HYDROPHOBIC COPOLYMER CARRYING SHORT CHAIN FATTY ACID ESTER UNIVERSITY OF TSUKUBA (JP) 2022-10-20 US disclosed
CN-115210219-A Oxime ester photoinitiators 巴斯夫欧洲公司 2022-10-18 CN disclosed
EP-4011444-A1 HYDROPHILIC-HYDROPHOBIC COPOLYMER CARRYING SHORT-CHAIN FATTY ACID ESTER University of Tsukuba (JP) 2022-06-15 EP disclosed
CN-114430756-A Hydrophilic-hydrophobic copolymers carrying short-chain fatty acid esters 国立大学法人筑波大学 2022-05-03 CN disclosed
US-20220121113-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2022-04-21 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
CN-1309561-C Photosensitive composition and photosensitive lithographic printing plate KODAK POLYCHROME GRAPHICS CO (US) 2007-04-11 CN disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US disclosed
WO-2006037728-A1 USE OF PYRIMIDO[5,4-G]PTERIDINES AS SHADING COMPONENT IN COLOR FILTER COLORANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-04-13 WO disclosed
WO-2006024617-A1 COMPOSITIONS CONTAINING ANTHRAQUINONE DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006024618-A1 CYANOPYRIDINE-BASED AZO DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006024619-A1 COMPOSITIONS CONTAINING PHTHALOCYANINE DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 WO disclosed
WO-2006018405-A1 OXIME ESTER PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-23 WO disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP disclosed
CN-1604849-A Photosensitive composition and photosensitive planographic printing plate KODAK POLYCHROME GRAPHICS CO (US) 2005-04-06 CN disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HDAC1 2523/4885HDAC3 2181/4885HDAC2 2426/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 HDAC1 2523/4885HDAC3 2181/4885HDAC2 2426/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 HDAC1 4446/4885HDAC3 4172/4885HDAC2 3972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.