SCHEMBL19474397

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc(-n5c6ccccc6c6ccc7c8ccccc8n(-c8ccc(-c9ccc(-c%10cccc(-c%11cccc(-c%12ccc(-c%13nc(-c%14ccc(-c%15ccc(-c%16ccc(-c%17ccc(-c%18nc(-c%19ccccc%19)nc(-c%19ccc(-n%20c%21ccccc%21c%21ccc%22c%23ccccc%23n(-c%23ccc(-c%24ccccc%24)cc%23)c%22c%21%20)cc%19)n%18)cc%17)cc%16)cc%15)cc%14)nc(-c%14ccc(-n%15c%16ccccc%16c%16ccc%17c%18ccccc%18n(-c%18ccc(-c%19ccccc%19)cc%18)c%17c%16%15)cc%14)n%13)cc%12)c%11)c%10)cc9)cc8)c7c65)cc4)n3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	KDM4E	B2RXH2	2/20	0.42

▸	ATM	Q13315	2/20	0.42

▸	L3MBTL1	Q9Y468	2/20	0.42

▸	NR3C1	P04150	1/20	0.37

▸	KMT2A	Q03164	5/20	0.36

▸	MEN1	O00255	4/20	0.36

▸	MAPT	P10636	3/20	0.36

▸	ALDH1A1	P00352	2/20	0.36

▸	HPGD	P15428	2/20	0.36

▸	HDAC4	P56524	1/20	0.36

▸	RXRA	P19793	1/20	0.36

▸	LMNA	P02545	1/20	0.35

▸	GLA	P06280	1/20	0.35

▸	AVPR1A	P37288	1/20	0.35

▸	HSP90AA1	P07900	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19474357	1.00	KDM4E (0.42)	KDM4EATML3MBTL1NR3C1KMT2A
SCHEMBL17809103	1.00	KDM4E (0.42)	KDM4EATML3MBTL1NR3C1KMT2A
SCHEMBL22596033	0.97	L3MBTL1 (0.44)	KDM4EATML3MBTL1NR3C1KMT2A
SCHEMBL21365578	0.97	L3MBTL1 (0.44)	KDM4EATML3MBTL1NR3C1KMT2A
SCHEMBL21365573	0.97	L3MBTL1 (0.44)	KDM4EATML3MBTL1NR3C1KMT2A
SCHEMBL24691501	0.96	KDM4E (0.39)	KDM4EATML3MBTL1NR3C1KMT2A
SCHEMBL24691494	0.96	KDM4E (0.39)	KDM4EATML3MBTL1NR3C1KMT2A
SCHEMBL19474386	0.96	KDM4E (0.39)	KDM4EATML3MBTL1NR3C1KMT2A
SCHEMBL24549519	0.96	KDM4E (0.39)	KDM4EATML3MBTL1NR3C1KMT2A
SCHEMBL19474338	0.96	KDM4E (0.39)	KDM4EATML3MBTL1NR3C1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2866273-B1	Organic electrolumiescent materials and devices	UNIVERSAL DISPLAY CORP (US)	2017-10-18	—	—	EP	disclosed