Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550856 | 0.82 | ALDH1A1 (0.42) | ALDH1A1ATML3MBTL1LMNATHRB | |
| SCHEMBL243344 | 0.82 | — | — | |
| SCHEMBL157088 | 0.80 | — | — | |
| SCHEMBL11392166 | 0.75 | — | — | |
| SCHEMBL6986795 | 0.73 | MAPT (0.59) | ALDH1A1ATML3MBTL1LMNATHRB | |
| SCHEMBL14761253 | 0.72 | ALDH1A1 (0.44) | ALDH1A1ATML3MBTL1LMNATHRB | |
| SCHEMBL3682633 | 0.72 | — | — | |
| SCHEMBL7082252 | 0.68 | ALDH1A1 (0.41) | ALDH1A1ATML3MBTL1LMNATHRB | |
| SCHEMBL10534064 | 0.67 | MAPT (0.48) | ALDH1A1ATML3MBTL1LMNATHRB | |
| SCHEMBL10419063 | 0.67 | MAPT (0.48) | ALDH1A1ATML3MBTL1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647725-B2 | Anti-infective 2-aminothiophenes | THE UNIVERSITY OF TOLEDO (US) | 2020-05-12 | — | — | US | claimed |
| US-20190119296-A1 | Anti-Infective 2-Aminothiophenes | THE UNIVERSITY OF TOLEDO (US) | 2019-04-25 | — | — | US | claimed |
| WO-2017184947-A1 | ANTI-INFECTIVE 2-AMINOTHIOPHENES | THE UNIVERSITY OF TOLEDO (US) | 2017-10-26 | — | — | WO | claimed |
| CN-114573485-A | Method for synthesizing alkynyl alkyl thioether | 华南理工大学 | 2022-06-03 | — | — | CN | disclosed |
| US-10647725-B2 | Anti-infective 2-aminothiophenes | THE UNIVERSITY OF TOLEDO (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190119296-A1 | Anti-Infective 2-Aminothiophenes | THE UNIVERSITY OF TOLEDO (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2017184947-A1 | ANTI-INFECTIVE 2-AMINOTHIOPHENES | THE UNIVERSITY OF TOLEDO (US) | 2017-10-26 | — | — | WO | disclosed |
| CN-102827167-A | Octahydro-pyrrolo [3,4-b ] pyrrole derivatives and their use as histamine-3 receptor ligands | ABBOTT LAB | 2012-12-19 | — | — | CN | disclosed |
| CN-1059439-C | Arylthiadiazolones with herbicidal activity | ISAGRO RICERCA SRL (IT) | 2000-12-13 | — | — | CN | disclosed |
| CN-1160046-A | Arylthiadiazolones with herbicidal activity | ISAGRO RICERCA SRL (IT) | 1997-09-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119296-A1 | Anti-Infective 2-Aminothiophenes | TST, ABAT, TPMT | ALDH1A1 2316/4885ATM 3936/4885L3MBTL1 507/4885 |
| US-10647725-B2 | Anti-infective 2-aminothiophenes | TST, ABAT, TPMT | ALDH1A1 2316/4885ATM 3936/4885L3MBTL1 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.