Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231009 | 0.82 | — | — | |
| SCHEMBL19475102 | 0.82 | ALDH1A1 (0.55) | ALDH1A1ATML3MBTL1LMNATHRB | |
| SCHEMBL27488323 | 0.80 | — | — | |
| SCHEMBL243344 | 0.68 | — | — | |
| SCHEMBL3247663 | 0.66 | — | — | |
| SCHEMBL1058399 | 0.66 | — | — | |
| SCHEMBL157088 | 0.66 | — | — | |
| SCHEMBL1058397 | 0.66 | — | — | |
| Benzene SCHEMBL28149441 | 0.66 | KDM4E (0.41) | ALDH1A1L3MBTL1LMNARAB9ANPC1 | |
| Ammonia Solution, Strong SCHEMBL27266542 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1767535-A1 | Synthesis of epothilones, intermediates thereto, analogues and uses thereof | Sloan-Kettering Institute For Cancer Research (US) | 2007-03-28 | — | — | EP | disclosed |