Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28169221 | 0.85 | FABP5 (0.49) | FABP5ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL19475149 | 0.83 | FABP5 (0.49) | FABP5ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL2308927 | 0.81 | FABP5 (0.53) | FABP5ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL2882948 | 0.80 | MEN1 (0.54) | FABP5ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL18674157 | 0.79 | FABP5 (0.49) | FABP5ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL6983292 | 0.77 | LMNA (0.63) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL13609760 | 0.76 | MEN1 (0.50) | FABP5ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL6859446 | 0.76 | FABP5 (0.46) | FABP5ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL28624547 | 0.76 | FABP5 (0.46) | FABP5ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL16005654 | 0.76 | FABP5 (0.49) | FABP5ALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289950-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1289972-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096323-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001096296-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |