Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520094 | 0.92 | MMP3 (0.44) | CA2CA1MMP3MMP9EPHX1 | |
| SCHEMBL31520085 | 0.92 | MMP3 (0.44) | CA2CA1MMP3MMP9EPHX1 | |
| SCHEMBL24040349 | 0.87 | CA1 (0.39) | CA2CA1TLR8DPP7MMP3 | |
| SCHEMBL12961905 | 0.87 | CA1 (0.39) | CA2CA1TLR8DPP7MMP3 | |
| SCHEMBL14819937 | 0.85 | CA2 (0.42) | CA2CA1DPP7SLC15A1MMP3 | |
| Hydrochloric Acid SCHEMBL8527464 | 0.84 | FOLH1 (0.38) | CA2CA1TLR8DPP7DPP8 | |
| SCHEMBL15834023 | 0.84 | FOLH1 (0.45) | CA1DPP7DPP8DPP9 | |
| SCHEMBL8976019 | 0.84 | MMP3 (0.35) | CA2CA1TLR8MMP3MMP9 | |
| SCHEMBL12743627 | 0.84 | CA2 (0.47) | CA2CA1TLR8DPP7SLC15A1 | |
| SCHEMBL6010230 | 0.82 | CA1 (0.46) | CA2CA1TLR8DPP7SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081880-A1 | COMPOSITIONS TARGETING SENESCENT CELLS AND THE USES THEREOF | BIOVENTURES, LLC (US) | 2020-04-23 | — | — | WO | disclosed |
| WO-2017184995-A1 | COMPOUNDS THAT INDUCE DEGRADATION OF ANTI-APOPTOTIC BCL-2 FAMILY PROTEINS AND THE USES THEREOF | BIOVENTURES, LLC (US) | 2017-10-26 | — | — | WO | disclosed |