Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.37 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16052301 | 0.76 | LPL (0.40) | GCKBRD4CREBBPIGLV6-57FFAR1 | |
| SCHEMBL19478356 | 0.74 | FFAR1 (0.39) | GCKBRD4CREBBPIGLV6-57FFAR1 | |
| SCHEMBL15716509 | 0.74 | LRRK2 (0.41) | IGLV6-57FFAR1ALKBH1ADRA2AADRA2B | |
| SCHEMBL15716702 | 0.70 | FFAR1 (0.40) | GCKIGLV6-57FFAR1ALKBH1ADRA2A | |
| SCHEMBL28048770 | 0.68 | CFTR (0.48) | ADRA2AADRA2BADRA2C | |
| SCHEMBL4363303 | 0.66 | FFAR1 (0.56) | IGLV6-57FFAR1KCNH2SCN3AADRA2A | |
| SCHEMBL9946121 | 0.66 | MEN1 (0.46) | — | |
| SCHEMBL6904351 | 0.66 | FFAR1 (0.61) | IGLV6-57FFAR1KCNH2SCN3AADRA2A | |
| SCHEMBL1203044 | 0.65 | FFAR1 (0.39) | GCKIGLV6-57FFAR1ALKBH1ADRA2A | |
| SCHEMBL1203174 | 0.65 | FFAR1 (0.39) | GCKIGLV6-57FFAR1ALKBH1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970323-B1 | FUROPYRIDINES AS BROMODOMAIN INHIBITORS. | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO 2) LTD (GB) | 2017-10-18 | — | — | EP | disclosed |